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In this regard, the livers of mice which are resistant to the hepatoxic effects of AFB 1 contain high concentrations of a Yc-type GST subunit [55] that has considerable GSH conjugating activity towards AFB 1 -epoxide [34], [37], [10], [9]

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Alcohol, particularly red wine, increases endogenous histamine release and competes with acetaldehyde dehydrogenase (ALDH) to retard histamine metabolism, thereby raising histamine levels