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A few caveats worth naming: the vote is non-binding, the FDA’s own scientists opposed all seven citing thin clinical data, and any formal reclassification still has to go through rulemaking — which could take until 2028

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Transcriptome analysis of pathway enrichment (Supplemental Figure 6A) and gene set enrichment analysis (GSEA) Supplemental Figure 6B) indicated that the hallmark pathway of glutamine family amino acid metabolic process was among the top-ranking upregulated gene sets in A2ARi-treated cells