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Both cellular and animal studies have demonstrated that YQFM significantly inhibits myocardial ferroptosis and the xCT/GPX4 axis, resulting in SIC amelioration ( 5.2.5 Traditional Chinese medicine in antioxidant therapy Traditional Chinese medicinal preparations containing active ingredients such as ginsenosides and Panax ginseng saponins have demonstrated significant protective effects in CHD

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Sheehan et al., 1989