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While researchers note that the LD50 (lethal dose) for GHK-Cu in murine models equates to an impossibly massive single dose of roughly 23,000mg for a 70kg human adult—rendering acute lethal toxicity highly improbable at the standard aesthetic therapeutic doses of 5-50mg—the long-term cumulative effects of daily copper peptide injections remain entirely unmapped in human populations

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The profound and rapid depletion of B cells that arises after treatment with these mAbs is then followed by repletion of lymphocytes with a more regulatory phenotype