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August 7, 2025 6:42 View More ➡ Why Synthroid Isn’t Working – The Shocking Truth About T4, T3 & Thyroid Symptoms with McCall McPherson In this episode of Modern Thyroid Wellness, McCall McPherson unpacks one of the most common frustrations in thyroid care: why levothyroxine-based medications (like Synthroid) often leave patients feeling unwell, even when their labs look “normal.” Drawing from her own experience as a thyroid patient and her extensive clinical work, McCall explains the flawed assumption that every body seamlessly converts T4 into active T3—and why that’s simply not the case for many people