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on the other hand, the reduced form of CoQ 10 (CoQ 10 -H 2 ) is a potent lipophilic antioxidant, which can capture LOO· to prevent the spread of free radical chain reaction and inhibit the production of LOOHs, and meanwhile the CoQ 10 -H 2 is oxidized ( 10 synthesis will disrupt GPX4 synthesis and CoQ 10 -H 2 antioxidant activity respectively, and eventually induce ferroptosis