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2 Effects and mechanism of natural products in acetaminophen-induced hepatotoxicity A number of phytochemicals have been identified to have hepatoprotective activity, such as silymarin for the treatment of liver poisoning, chronic hepatitis and cirrhosis (Abenavoli et al., 2018), resveratrol and curcumin for the relief of liver damage, etc., (McGill et al., 2015

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Once-daily administration is common, with many users opting for evening dosing approximately 60–90 minutes after their final meal