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Effect of Dietary Coenzyme Q10 Plus NADH Supplementation on Fatigue Perception and Health-Related Quality of Life in Individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial

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This demonstrated that the α-MSH-MC1R signaling pathway induces melanin production predominantly by elevating intracellular cAMP levels, and the inhibition of which can exert inhibitory effects on melanogenesis