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Most people notice inflammation, stiffness, and swelling ease first, often alongside digestive comfort (weeks 1–2), then real mobility and faster recovery between sessions (weeks 2–4), then structural improvement with skin and connective-tissue changes becoming visible (weeks 4–8), and a return to full activity from week 8 onward

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For example, adding 1mL more to an existing 2mL reconstitution gives you 3mL total, yielding a 3.33mg/mL concentration