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The hippocampal atrophy observed in chronic depression corresponds to reduced BDNF signaling and impaired neurogenesis

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### Discard the Vial If: - It has been more than 30 days since reconstitution - You see cloudiness, particles, or color changes - The vial was left at room temperature for more than a few hours - You suspect contamination (e.g., the stopper was touched without cleaning) When in doubt, discard and start fresh

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