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The measurements that were used to determine the outcomes were: pain (VAS score) and functional scores (e.g Constant-Murley, ASES, SST) Results Pain reduction (VAS score) PRP showed to be somewhat better in the short term but had similar scores to corticosteroids on the remaining time marks, with the difference between them being insignificant, also, PRP showed to be more effective than Corticosteroids in improving function, particularly as time went on, the difference became more apparent (at 3-6 weeks, the mean difference was -3.97, after 24 weeks, it became 9.85 Constant-Murley) Conclusion When comparing between corticosteroids and PRP, there is no significant difference between them regarding pain reduction, yet, PRP has proven its effectiveness over the long-term for functional improvement, and which means that it could see more clinical use provided that it is cost-effective, yet more research is required to reach a final judgment and thorough evaluation due to the heterogeneity found in the studies Keywords: Rotator cuff, platelet-rich plasma, corticosteroid INTRODUCTION Rotator cuff injuries are among the most prevalent causes of shoulder pain and disability, particularly affecting two distinct populations: older adults with age-related degenerative tears and younger individuals—especially athletes—with traumatic or overuse-related injuries
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See Full Answer "Best" dose is always individual, but here is a quote from a frequently cited study that will help explain things: "In healthy eugonadal men selected to unde
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