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Peptide solutions are generally stable for up to 30 days when refrigerated at 4°C (39°F) Stability depends on peptide length, amino acid composition, and inherent instability factors Long-Term Storage If peptides must be stored in solution for extended periods: Use sterile buffers with a pH between 5 and 6 when possible Divide solutions into small aliquots to prevent repeated freeze-thaw cycles Store frozen at −80°C (−112°F) for maximum stability Repeated thawing and refreezing should be avoided, as it accelerates peptide breakdown

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Similar observations were made in aortic tissue slices, where FOXO4-DRI treatment led to increased expression of p-P53, mainly localized in the cytoplasm (Figures 5F,G)