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The aim of this study was to evaluate oxidative stress markers (extracellular thiol-disulfide homeostasis and intracellular glutathione homeostasis) in patients with hypothyroidism due to autoimmune (Hashimoto’s thyroiditis) or nonautoimmune thyroid disease rendered euthyroid after levothyroxine replacement

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Despite the limitations of over-expression paradigms, one can conclude from these results that LRRK2 has an important role in mitochondrial function and in the capacity of the cell to keep oxidative stress in check