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However, interpretation remains cautious, as reproductive endpoints (ongoing pregnancy, live birth) are inconsistently reported and dosing (commonly 2–4 g/day), formulations (MI alone vs 40:1 MI: DCI), co-therapies, and trial quality vary widely, prompting calls for larger, standardized, phenotype-stratified studies

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A study found that 12 weeks of consistent collagen consumption significantly reduced wrinkles and fine lines by 35%