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By inhibiting NNMT, 5-Amino-1MQ prevents the age-associated drain on NAD+ pools, effectively maintaining cellular NAD+ availability at more youthful levels

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Further, PS exposure of uninfected erythrocytes and increased levels of anti-PS auto-antibodies have been proposed as key mechanisms leading to the loss of non-infected erythrocytes, therefore contributing to malarial anemia (Totino et al., 2010