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Signs that warrant medical attention: Erythema spreading beyond 5cm from the injection site, particularly if accompanied by warmth and swelling — this pattern is consistent with early cellulitis Purulent discharge from the injection site Fever within 24–48 hours of injection A firm, tender nodule that persists beyond 72 hours and is growing rather than resolving If you aspirate blood into the syringe before injection — visible blood drawing back into the barrel when you pull the plunger slightly — withdraw the needle, discard the syringe, and prepare a new one