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[52] Despite the promising results in preclinical studies, there are still challenges that need to be addressed before translation into the clinic, including the identification of the optimal peptide targets and delivery methods, as well as the potential off-target effects and long-term safety

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By contrast, a tear involving the distal insertion of the biceps is most often the result of trauma due to overloading, is acutely painful, and results in weakness in the elbow joint

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