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[DOI] [PubMed] [Google Scholar] 24.Capra A.P., Crupi L., Panto G., Repici A., Calapai F., Squeri R., Ardizzone A., Esposito E

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DED pathophysiology includes an excess of inflammatory cytokines that increase reactive oxygen species (ROS) production, leading to a disruption of the balance between the antioxidant and the prooxidant systems, damaging the healthy tear film (Dogru et al., 2018)