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These are a few examples of how targeted nutritional interventions can influence melatonin production, circadian timing, and sleep parameters, particularly in middle-aged and older adults

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Table 1 includes larger published prospective studies evaluating the association of TMAO and adverse outcomes (cardiovascular-related and mortality-related) in CVD-free individuals, patients with CVD or coronary artery disease (CAD), patients with acute coronary syndrome (ACS), and patients with chronic kidney disease (CKD)