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However, some animal research suggests the peptide retains activity in the GI tract even after exposure to digestive conditions, possibly because part of its mechanism is local mucosal signaling rather than systemic absorption

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Immunohistochemical staining by an automated immunostainer (Dako Autostainer Plus, DakoCytomation, Glostrup, Denmark) was performed using LSAB HRP and HRP+ kits according to the manufacturer’s instructions