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injection two days before UUO induction and continued for a week after UUO, UUO-induced renal dysfunction, oxidative stress, and production of nitric oxide and transforming factor-1 were greatly attenuated by ALA treatment [88]

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Secondary antioxidants are externally provided from dietary sources, such as vitamins (vitamins A, C and E), minerals (selenium, zinc, copper and manganese) and other substances, including polyphenols found in grapes and green tea